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The stage is set for a compelling top-flight matchup as front-runners Arsenal host bottom-placed Wolverhampton Wanderers to the their home ground.

Confirmed Sides

Mikel Arteta's side have opted for a trio of alterations from the side that suffered a 2-1 defeat at Villa Park in their previous outing. The French defender, Viktor Gyökeres and the Brazilian winger all come into the starting eleven. Martin Ødegaard and the Spanish midfielder drop to the bench, while Riccardo Calafiori is absent. Saliba is back after sitting out five matches due to injury.

The visitors also make three changes to their lineup after being soundly beaten 4-1 at Molineux by United on Monday evening. The experienced full-back, João Gomes and the South Korean forward come in. Ki-Jana Hoever and Jhon Arias are on the substitutes, while Jean‐Ricner Bellegarde misses out altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Bench: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
VAR Official: John Brooks

Preamble

Good evening! And I mean, c’mon …

The table paints a striking contrast. The hosts sit comfortably at the top of the table, while their opponents prop up the league.

… yet while this will be the 42nd occasion the Premier League leaders have faced the side propping up the entire table – winning 30 victories from 41, with seven draws – which team is behind two of the four all-time upsets? Why, Wolves, of course! Therefore, although Mikel Arteta will undoubtedly be expecting another three points, the Wolves boss must know that long shots occasionally find the target, and you never know. Kick-off is at 8pm GMT. Let's go!

^{(The other two bottom-beats-top wins in the modern top-flight era are Oldham’s 1-0 win over United in March 1993, and Tottenham Hotspur – yeah, a surprising one - defeating Liverpool in November 2008.)}